Research
Cellular
High-dose oral intake of N-acetyl-L-cysteine (NAC) significantly attenuates cellular oxidation associated with strenuous exercise.
NAC may be an effective nutritional intervention for reducing oxidative stress during strenuous exercise.
StrongSupportsmedium confidence
Time-dependent changes in global metabolism of filtered red blood cell lysates by CE-ESI-MS were measured to reveal a significant attenuation of cellular oxidation associated with high-dose oral NAC intake relative to a control.
Why this rating
Based on the study design involving a controlled exercise protocol and metabolomics analysis.
Source
Differential Metabolomics for Quantitative Assessment of Oxidative Stress with Strenuous Exercise and Nutritional Intervention: Thiol-Specific Regulation of Cellular Metabolism with <i>N</i>-Acetyl-<scp>l</scp>-Cysteine Pretreatment
Richard Lee et al. · Analytical Chemistry · 2010
DOI 10.1021/ac9029746
other · n=1Cited 80×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
Related findings · Cellular
- Athletes aiming to reduce fat mass and preserve FFM should consume protein intakes in the range of ∼1.8-2.7 g kg(-1) d(-1).Strong
- A minimum daily protein intake of ≥1.6 g/kg is necessary to observe significant improvements in muscle mass from whey protein supplementation.Strong
- Most athletes ideally need 1.2 to 2.0 grams/kg of body weight/day of protein, preferably split across 3-4 meals.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →