Research
Metabolic adaptation
Each 5% increment in energy from LA intake was associated with a 10% lower risk of T2DM.
Increasing energy intake from linoleic acid could further lower the risk of type 2 diabetes.
StrongSupportsmedium confidence
In the dose-response analysis, each 5% increment in energy from LA intake was associated with a 10% lower risk of T2DM.
Why this rating
Based on a systematic review and meta-analysis of prospective cohort studies.
Source
Dietary Intake of Linoleic Acid, Its Concentrations, and the Risk of Type 2 Diabetes: A Systematic Review and Dose-Response Meta-analysis of Prospective Cohort Studies
Seyed Mohammad Mousavi et al. · Diabetes Care · 2021
DOI 10.2337/dc21-0438
Meta-analysisCited 80×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- High intake of linoleic acid (LA) was associated with a 6% lower risk of type 2 diabetes mellitus (T2DM) (summary relative risk [RR] 0.94, 95% CI 0.90, 0.99).Strong
- Elevated concentrations of LA in the body were significantly associated with a lower risk of T2DM (summary RR 0.85, 95% CI 0.80, 0.90).Strong
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