Metabolic adaptation

Elevated concentrations of LA in the body were significantly associated with a lower risk of T2DM (summary RR 0.85, 95% CI 0.80, 0.90).

Monitoring and increasing body concentrations of linoleic acid may help reduce diabetes risk.

StrongSupportsmedium confidence

The summary RR for diabetes per SD increment in LA concentrations in adipose tissue/blood compartments was 0.85 (95% CI 0.80, 0.90; I2 = 66.2%).

Seyed Mohammad Mousavi et al. · Diabetes Care · 2021

Why this rating

Based on a systematic review and meta-analysis of prospective cohort studies.

Source

Dietary Intake of Linoleic Acid, Its Concentrations, and the Risk of Type 2 Diabetes: A Systematic Review and Dose-Response Meta-analysis of Prospective Cohort Studies

Seyed Mohammad Mousavi et al. · Diabetes Care · 2021

Meta-analysisCited 80×

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