Research
Metabolic adaptation
Plasma TMAO and related metabolites were not significantly associated with type 2 diabetes risk.
The findings suggest that TMAO and related metabolites may not be useful biomarkers for predicting type 2 diabetes risk.
StrongRefutesmedium confidence
In multivariable analyses, TMAO and metabolites were not significantly associated with type 2 diabetes risk.
Why this rating
Based on the prospective cohort study design.
Source
Association of Trimethylamine<i>N</i>-Oxide and Related Metabolites in Plasma and Incident Type 2 Diabetes
Rozenn N. Lemaître et al. · JAMA Network Open · 2021
DOI 10.1001/jamanetworkopen.2021.22844
cohort · n=4442Cited 69×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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