Research
Molecular
Higher levels of linoleic acid (LA) were associated with lower cardiovascular mortality with a hazard ratio of 0.78 (95% CI, 0.70-0.85).
Higher linoleic acid intake may contribute to reduced cardiovascular mortality.
StrongSupportsmedium confidence
Higher levels of LA were significantly associated with lower risks of total CVD, cardiovascular mortality, and ischemic stroke, with hazard ratios per interquintile range of 0.78 (0.70-0.85).
Why this rating
Based on a meta-analysis of 30 prospective studies.
Source
Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality.
Matti Marklund et al. · Apollo (University of Cambridge) · 2019
DOI 10.17863/cam.36839
Meta-analysisCited 51×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Higher levels of linoleic acid (LA) were significantly associated with lower risks of total cardiovascular disease (CVD) with a hazard ratio of 0.93 (95% CI, 0.88-0.99).Strong
- Arachidonic acid (AA) levels were not associated with higher risk of cardiovascular outcomes, and higher levels were associated with lower risk of total CVD with a hazard ratio of 0.92 (95% CI, 0.86-0.99).Strong
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