Research
Molecular
Arachidonic acid (AA) levels were not associated with higher risk of cardiovascular outcomes, and higher levels were associated with lower risk of total CVD with a hazard ratio of 0.92 (95% CI, 0.86-0.99).
Arachidonic acid may not increase cardiovascular risk and could be beneficial at higher levels.
StrongQualifiesmedium confidence
AA levels were not associated with higher risk of cardiovascular outcomes; in a comparison of extreme quintiles, higher levels were associated with lower risk of total CVD (0.92; 0.86-0.99).
Why this rating
Based on a meta-analysis of 30 prospective studies.
Source
Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality.
Matti Marklund et al. · Apollo (University of Cambridge) · 2019
DOI 10.17863/cam.36839
Meta-analysisCited 51×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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