Research
Energy balance
MIP supplements were not found to be superior when directly compared with protein-only (PRO) supplements.
Practitioners should consider that while MIP supplements are effective, they do not provide additional benefits over traditional protein-only supplements.
StrongRefutesmedium confidence
MIP supplements were not superior when directly compared with PRO supplements.
Why this rating
Based on a systematic review and meta-analysis of 35 trials.
Source
Do multi-ingredient protein supplements augment resistance training-induced gains in skeletal muscle mass and strength? A systematic review and meta-analysis of 35 trials
Kerry R O’Bryan et al. · British Journal of Sports Medicine · 2019
DOI 10.1136/bjsports-2018-099889
Meta-analysisCited 48×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Multi-ingredient protein (MIP) supplements combined with resistance exercise training lead to significant increases in fat-free mass (FFM) by 0.80 kg and improvements in 1-repetition maximum (1RM) lower body strength by 4.22 kg and upper body strength by 2.56 kg compared to non-MIP supplemented conditions.Strong
- MIP supplements show a greater effect on fat-free mass (FFM) in untrained individuals (0.95 kg) and older participants (0.77 kg) compared to trained individuals.Strong
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