Research
Energy balance
Weight, body mass index (BMI), fat, and fat-free mass significantly decreased at month 12 after caloric restriction (CR) vs control.
Caloric restriction can effectively reduce weight and body composition metrics in healthy individuals.
StrongSupportsmedium confidence
Weight, body mass index (BMI), fat, and fat-free mass (P < 0.001 for all) significantly decreased at month 12 after CR vs control.
Why this rating
Based on study design from abstract.
Source
EFFECTS OF 12 MONTHS OF CALORIC RESTRICTION ON MUSCLE MITOCHONDRIAL FUNCTION IN HEALTHY INDIVIDUALS
Lauren M. Sparks et al. · The Journal of Clinical Endocrinology & Metabolism · 2016
DOI 10.1210/jc.2016-3211
rct · n=51Cited 45×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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