Research
Metabolic adaptation
Model predictions of relative skeletal muscle changes with caloric restriction were validated in longitudinal studies.
The validation of these models can help practitioners predict muscle loss during caloric restriction more accurately.
StrongSupportsmedium confidence
Model predictions of relative SM changes with CR were evaluated in two longitudinal studies, one 12 to 14 weeks in duration (n = 74) and the other 12 months in duration (n = 26).
Why this rating
Based on the study design involving longitudinal monitoring and a large sample size.
Source
Proportion of caloric restriction‐induced weight loss as skeletal muscle
Steven B. Heymsfield et al. · Obesity · 2023
DOI 10.1002/oby.23910
cohort · n=897Cited 42×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Nonelderly males with overweight and obesity experience a reduction in skeletal muscle mass of about 2 to 2.5 kg per 10-kg weight loss during voluntary caloric restriction.Strong
- Nonelderly females with overweight and obesity experience a reduction in skeletal muscle mass of about 1 to 1.5 kg per 10-kg weight loss during voluntary caloric restriction.Strong
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