Research
Metabolic adaptation
High sugar intake is associated with greater CHD risk, with a hazard ratio (HR) of 1.09 per 50 g/day.
Reducing sugar intake may help lower the risk of coronary heart disease.
StrongSupportsmedium confidence
High sugar intake was associated with greater CHD risk [HR: 1.09 (95% CI: 1.02, 1.17) per 50 g/d].
Why this rating
Based on the large prospective cohort study design.
Source
Glycemic index, glycemic load, and risk of coronary heart disease: a pan-European cohort study
Sabina Sieri et al. · American Journal of Clinical Nutrition · 2020
DOI 10.1093/ajcn/nqaa157
cohort · n=338325Cited 37×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- High glycemic load (GL) is associated with greater coronary heart disease (CHD) risk, with a hazard ratio (HR) of 1.16 for the highest vs. lowest quintile and HR of 1.18 per 50 g/day of GL intake.Strong
- High available carbohydrate intake is associated with greater CHD risk, with a hazard ratio (HR) of 1.11 per 50 g/day.Strong
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