Energy balance
In obese patients with type 2 diabetes (BMI ≥30), intentional weight loss is associated with a statistically significant increase in all-cause mortality.
If you are obese (BMI ≥30) and have type 2 diabetes, intentional weight loss might actually increase your risk of death compared to maintaining your weight. Discuss this specific risk with your doctor, as standard weight loss advice may not apply to your long-term survival.
In these obese patients, intentional weight loss was associated with an increased mortality (HR 1.37, 95% CI 1.01–1.84, P = 0.04)
Why this rating
Subgroup analysis of a robust cohort study; statistical significance is present but confidence intervals are wide.
Source
Intentional Weight Loss and Longevity in Overweight Patients with Type 2 Diabetes: A Population-Based Cohort Study
Rasmus Køster‐Rasmussen et al. · PLoS ONE · 2016
DOI 10.1371/journal.pone.0146889
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