Research
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In the study, 8.7% of participants receiving GLP-1 RA had a cardiovascular event compared to 11.2% of those receiving placebo.
The data indicates a lower incidence of cardiovascular events with GLP-1 RA treatment.
StrongSupportsmedium confidence
During follow-up, 673 participants receiving GLP-1 RA treatment (8.7%) and 416 participants receiving placebo (11.2%) had a cardiovascular event.
Why this rating
Based on a meta-analysis of placebo-controlled randomized controlled trials.
Source
Effect of glucagon‐like peptide‐1 receptor agonists on cardiovascular events in overweight or obese adults without diabetes: A meta‐analysis of placebo‐controlled randomized trials
Ana Rita Leite et al. · Diabetes Obesity and Metabolism · 2022
DOI 10.1111/dom.14707
Meta-analysisCited 34×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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