Research
Metabolic adaptation
>10% weight loss is associated with cardiovascular mortality (HR, 2.76; 95% CI, 1.87-4.09) in patients with type 2 diabetes.
>10% weight loss in patients with type 2 diabetes may indicate a higher risk of cardiovascular mortality.
StrongSupportsmedium confidence
Over the following 3 years of the trial, >10% weight loss was strongly associated with cardiovascular mortality (HR, 2.76; 95% CI, 1.87-4.09),
Why this rating
Based on study design from abstract.
Source
The Risks of Cardiovascular Disease and Mortality Following Weight Change in Adults with Diabetes: Results from ADVANCE
Alexandra K. Lee et al. · The Journal of Clinical Endocrinology & Metabolism · 2019
rct · n=10081Cited 34×
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