Research
Metabolic adaptation
Fat oxidation and ketogenesis increased in both groups, with significantly greater increases in the SAR425899 group (p < 0.05).
SAR425899 may enhance fat metabolism, which could support weight loss efforts.
StrongSupportsmedium confidence
Fat oxidation and ketogenesis increased in both groups, with significantly greater increases with SAR425899 (p < 0.05).
Why this rating
Based on the randomized controlled trial design.
Source
<scp>Glucagon‐like peptide</scp>‐1/glucagon receptor agonism associates with reduced metabolic adaptation and higher fat oxidation: A randomized trial
Karen D. Corbin et al. · Obesity · 2023
rct · n=35Cited 26×
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