Research
Energy balance
There was no difference in mean total body weight change between IBD and non-IBD cohorts after semaglutide initiation.
Weight loss outcomes with semaglutide appear consistent regardless of IBD status.
StrongSupportsmedium confidence
There was no difference in mean TBW change after initiation of semaglutide in the IBD and non-IBD cohorts (-16 ± 13.4 pounds vs -18 ± 12.7 pounds; P = .24).
Why this rating
The study is a retrospective cohort study using a large database.
Source
Effectiveness and Safety of Semaglutide for Weight Loss in Patients With Inflammatory Bowel Disease and Obesity
Aakash Desai et al. · Inflammatory Bowel Diseases · 2024
DOI 10.1093/ibd/izae090
cohort · n=47424Cited 27×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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