Research
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There was no increased risk of IBD-specific adverse events associated with semaglutide use.
Semaglutide can be considered safe for use in IBD patients without increasing the risk of adverse events.
StrongSupportsmedium confidence
There was no difference in the risk of oral or intravenous steroid use and any-cause hospitalization in the semaglutide group compared with the group without semaglutide use in patients with IBD.
Why this rating
The study is a retrospective cohort study using a large database.
Source
Effectiveness and Safety of Semaglutide for Weight Loss in Patients With Inflammatory Bowel Disease and Obesity
Aakash Desai et al. · Inflammatory Bowel Diseases · 2024
DOI 10.1093/ibd/izae090
cohort · n=47424Cited 27×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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