Research
Metabolic adaptation
A form of Mfn2 lacking transmembrane domains stimulates glucose oxidation in mouse skeletal muscle.
This suggests that targeting Mfn2 could enhance glucose metabolism in muscle.
StrongSupportsmedium confidence
The expression of ΔMfn2 in mouse skeletal muscle stimulated glucose oxidation.
Why this rating
Based on the experimental findings presented in the abstract.
Source
A form of mitofusin 2 (Mfn2) lacking the transmembrane domains and the COOH-terminal end stimulates metabolism in muscle and liver cells
Jessica Segalés et al. · American Journal of Physiology-Endocrinology and Metabolism · 2013
otherCited 27×
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