Research

Metabolic adaptation

Tirzepatide induced a mean absolute HbA1c reduction across the three doses ranging from 2.3% to 3.0% in East Asian participants with type 2 diabetes.

Tirzepatide is effective in reducing HbA1c levels in East Asian individuals with type 2 diabetes.

StrongSupportsmedium confidence
Across all BMI and age subgroups, mean absolute HbA1c reductions across the three doses ranged from 2.3% to 3.0%.
Arihiro Kiyosue et al. · Diabetes Obesity and Metabolism · 2022

Why this rating

Based on the phase 3 clinical trial data presented in the abstract.

Source

Safety and efficacy analyses across age and body mass index subgroups in East Asian participants with type 2 diabetes in the phase 3 tirzepatide studies ( <scp>SURPASS</scp> programme)

Arihiro Kiyosue et al. · Diabetes Obesity and Metabolism · 2022

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