Research
Molecular
Fatty acids increase GDF15 levels dose dependently, with the greatest response observed with linolenic acid.
Incorporating fatty acids like linolenic acid may enhance GDF15 levels, potentially influencing dietary responses.
StrongSupportsmedium confidence
We found that fatty acids increase GDF15 levels dose dependently, with the greatest response observed with linolenic acid.
Why this rating
The study design indicates a direct investigation of the effects of fatty acids on GDF15.
Source
Fatty Acids Increase GDF15 and Reduce Food Intake Through a GFRAL Signaling Axis
Dongdong Wang et al. · Diabetes · 2023
DOI 10.2337/db23-0495
otherCited 22×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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