Research
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Benefits of the intervention were not evident for those entering the trial with a history of cardiovascular disease.
Practitioners should consider individual health histories when recommending lifestyle interventions.
StrongRefutesmedium confidence
Benefits were comparable for individuals grouped by baseline age and body mass index and sex but were not evident for those entering the trial with a history of cardiovascular disease.
Why this rating
Based on the randomized controlled trial design.
Source
Long-term Impact of a 10-Year Intensive Lifestyle Intervention on a Deficit Accumulation Frailty Index: Action for Health in Diabetes Trial
Joni K. Evans et al. · The Journals of Gerontology Series A · 2023
DOI 10.1093/gerona/glad088
rct · n=5145Cited 19×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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