Research
Molecular
MYOD1, MYF5, and MYF6 mean methylation was reduced after 4 and 8 hours in response to all exercise protocols.
Resistance, high-intensity interval, and concurrent exercise can effectively reduce DNA methylation in myogenic regulatory factors.
StrongSupportsmedium confidence
Compared with REST, MYOD1, MYF5, and MYF6, mean methylation across all CpGs analyzed was reduced after 4 and 8 h in response to all exercise protocols (P < 0.05).
Why this rating
Based on study design from abstract.
Source
Interrelated but Not Time-Aligned Response in Myogenic Regulatory Factors Demethylation and mRNA Expression after Divergent Exercise Bouts
Guilherme Defante Telles et al. · Medicine & Science in Sports & Exercise · 2022
other · n=9Cited 15×
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