Research
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Bariatric surgery is associated with substantial weight reduction (20-30%) and markedly lower subsequent risk for major adverse cardiovascular events (MACE).
Bariatric surgery may be a highly effective option for patients with obesity at risk for cardiovascular events.
StrongSupportsmedium confidence
Bariatric surgery is associated with substantial weight reduction (20-30%) and markedly lower subsequent risk for MACE.
Why this rating
The claim is based on a review of evidence regarding bariatric surgery outcomes.
Source
Pharmacotherapy for obesity: recent evolution and implications for cardiovascular risk reduction
Kevin C. Maki et al. · Expert Review of Endocrinology & Metabolism · 2023
DOI 10.1080/17446651.2023.2209176
reviewCited 14×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Lifestyle interventions and older antiobesity pharmacotherapies have been associated with less than 12% body weight reduction and no clear benefit to reduce MACE risk.Strong
- Newer antiobesity pharmacotherapies, particularly semaglutide and tirzepatide, have shown greater efficacy for weight reduction compared with older medications.Strong
Related findings · Energy balance
- Achieving a total body weight loss of 10-15% (or >10-15 kg) through Total Diet Replacement (TDR) induces remission of Type 2 Diabetes in individuals with short-duration disease.Strong
- Bariatric surgery is superior to medical management alone for inducing significant long-term weight loss, remission of type 2 diabetes, and reduction in mortality for patients with BMI ≥ 40 or ≥ 35 with comorbidities.Strong
- Achieving type 2 diabetes remission requires significant weight loss (≥15 kg) via major caloric restriction, independent of macronutrient composition.Strong
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