Research
Energy balance
Genetic predisposition to higher BMI does not predict weight regain after weight loss.
Genetic factors related to BMI may not be useful for predicting weight regain, focusing instead on abdominal obesity genetics.
StrongRefutesmedium confidence
Genetic predisposition to higher BMI or WHRadjBMI was not associated with weight regain after weight loss.
Why this rating
Based on the large sample size from the Look AHEAD study.
Source
Abdominal Obesity Genetic Variants Predict Waist Circumference Regain After Weight Loss
Malene Revsbech Christiansen et al. · Diabetes · 2023
DOI 10.2337/db23-0131
cohort · n=1415Cited 14×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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