Research
Energy balance
HU6 treatment significantly decreased total fat mass by -2.96 kg compared to placebo (P < .001).
HU6 may help reduce fat mass in patients with obesity-related HFpEF.
StrongSupportsmedium confidence
HU6 (vs placebo) significantly decreased total fat mass (between-group difference, -2.96 kg; P < .001).
Why this rating
Based on a randomized clinical trial design.
Source
Novel Controlled Metabolic Accelerator for Obesity-Related HFpEF
Ambarish Pandey et al. · JAMA Cardiology · 2025
rct · n=66Cited 12×
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