Research
Molecular
Metabolic dysregulation is linked to ectopic fat deposition and alterations in immune cell populations in adipose tissue among PWH.
Understanding these links can help in developing targeted interventions for obesity in PWH.
StrongSupportsmedium confidence
Metabolic dysregulation has also been linked to ectopic fat deposition and alterations in innate and adaptive immune cell populations in adipose tissue that accompany HIV and obesity.
Why this rating
The claim is supported by recent studies linking metabolic dysregulation to specific physiological changes.
Source
The pathogenesis of obesity in people living with HIV
Samuel Bailin et al. · Current Opinion in HIV and AIDS · 2023
DOI 10.1097/coh.0000000000000834
reviewCited 12×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Obesity accompanies an increasing burden of metabolic disease among people living with HIV (PWH).Strong
- Contemporary antiretroviral therapy (ART) regimens, particularly integrase strand transfer inhibitors (INSTIs) and tenofovir alafenamide (TAF), are contributors to weight gain and obesity in PWH.Strong
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