Research
Cellular
Contemporary antiretroviral therapy (ART) regimens, particularly integrase strand transfer inhibitors (INSTIs) and tenofovir alafenamide (TAF), are contributors to weight gain and obesity in PWH.
Clinicians should consider the impact of specific ART regimens on weight management in PWH.
StrongSupportsmedium confidence
Several observational and experimental studies... have evaluated the role of contemporary ART regimens, particularly integrase strand transfer inhibitors (INSTIs) and tenofovir alafenamide (TAF), as contributors to weight gain, obesity, and cardiometabolic disease.
Why this rating
The claim is based on recent observational and experimental studies.
Source
The pathogenesis of obesity in people living with HIV
Samuel Bailin et al. · Current Opinion in HIV and AIDS · 2023
DOI 10.1097/coh.0000000000000834
reviewCited 12×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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