Research
Energy balance
Participants lost nearly 40% of their initial body weight (38% ± 9%), with 17% from fat-free mass (FFM) and 83% from fat.
Practitioners should note the significant fat loss compared to FFM loss in weight management programs.
StrongSupportsmedium confidence
By week 30, participants lost nearly 40% of their initial body weight (38% ± 9%), 17% from FFM and 83% from fat.
Why this rating
Based on the observational study design with clear measurements.
Source
Metabolic Slowing With Massive Weight Loss Despite Preservation of Fat-Free Mass
Darcy L. Johannsen et al. · Obstetrical & Gynecological Survey · 2012
DOI 10.1097/01.ogx.0000423189.40994.eb
cohort · n=16Cited 11×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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