Research
Neural
High carbohydrate intake is associated with a higher risk of dementia (HR 1.48 (95%CI: 1.15-1.91)), while low carbohydrate intake is not significantly associated.
Practitioners should consider advising older adults to moderate their carbohydrate intake to potentially reduce dementia risk.
StrongSupportsmedium confidence
Compared to individuals with optimal carbohydrate intake, those with high intake (HR (95%CI): 1.48(1.15-1.91)) but not low intake (1.19(0.89-1.57)) had a higher risk of dementia.
Why this rating
Based on a large cohort study design.
Source
Macronutrient Intake and Risk of Dementia in Community-Dwelling Older Adults: A Nine-Year Follow-Up Cohort Study
Xianwen Shang et al. · Journal of Alzheimer s Disease · 2021
DOI 10.3233/jad-215042
cohort · n=93389Cited 9×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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