Research
Metabolic adaptation
The benefit of maintained fitness on cardiometabolic risk factors might be blunted by baseline insulin resistance.
Practitioners should consider baseline insulin resistance when evaluating fitness benefits.
StrongQualifiesmedium confidence
This benefit might be blunted by baseline IR.
Why this rating
Based on the prospective cohort study design.
Source
Fitness Change Effects on Midlife Metabolic Outcomes
Lisa S. Chow et al. · Medicine & Science in Sports & Exercise · 2014
DOI 10.1249/mss.0000000000000481
cohort · n=2048Cited 8×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Maintained fitness after 20 years was associated with a greater increase in HDL cholesterol and less increase in weight, waist girth, blood pressure, and triglycerides compared to decreased fitness.Strong
- Maintained fitness reduced the rate of incident diabetes in insulin sensitive participants but not in insulin resistant participants.Strong
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