Research
Molecular
3-methylhistidine and proline betaine concentrations increased consistently when participants were assigned a Prudent diet (q < 0.05) in both plasma and urine samples.
Practitioners can use these metabolites as biomarkers to monitor adherence to a Prudent diet.
StrongSupportsmedium confidence
Overall, 3-methylhistidine and proline betaine concentrations increased consistently when participants were assigned a Prudent diet (q < 0.05) in both plasma and urine samples.
Why this rating
Based on the randomized clinical trial design with robust metabolite profiling.
Source
Metabolic Trajectories Following Contrasting Prudent and Western Diets from Food Provisions: Robust Biomarkers of Short-Term Changes in Habitual Diet
Nadine Wellington et al. · Preprints.org · 2019
DOI 10.20944/preprints201908.0149.v1
rct · n=42Cited 8×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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