Research
Molecular
Creatinine-normalized urinary imidazole propionate, hydroxypipecolic acid, dihydroxybenzoic acid, and enterolactone glucuronide increased with a Prudent diet (p < 0.05).
These metabolites can serve as indicators for dietary adherence to a Prudent diet.
StrongSupportsmedium confidence
Similarly, creatinine-normalized urinary imidazole propionate, hydroxypipecolic acid, dihydroxybenzoic acid, and enterolactone glucuronide, as well as plasma ketoleucine and ketovaline increased with a Prudent diet (p < 0.05) after adjustments for age, sex and BMI.
Why this rating
The study design includes rigorous metabolite profiling in a randomized trial.
Source
Metabolic Trajectories Following Contrasting Prudent and Western Diets from Food Provisions: Robust Biomarkers of Short-Term Changes in Habitual Diet
Nadine Wellington et al. · Preprints.org · 2019
rct · n=42Cited 8×
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