Research
Energy balance
Semaglutide reduces percentage body weight by a mean difference of -10.73 (95% CI -12.24 to -9.21) at medium-term follow-up.
Semaglutide can be an effective treatment option for weight loss in adults with obesity.
StrongSupportsmedium confidence
At medium-term follow-up, semaglutide reduces percentage body weight (mean difference (MD) -10.73, 95% confidence interval (CI) -12.24 to -9.21; 15 studies, 8651 participants; high-certainty evidence).
Why this rating
Based on meta-analysis of randomized controlled trials.
Source
Semaglutide for adults living with obesity
Javier Bracchiglione et al. · Cochrane Database of Systematic Reviews · 2025
Meta-analysisCited 7×
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