Research
Molecular
The engineered GLP-1 receptor agonist depot offers a more convenient and long-lasting therapeutic option for managing diabetes and treating metabolic disorders.
This approach could simplify treatment regimens for patients with diabetes.
StrongSupportsmedium confidence
The formation of supramolecular nanofiber depots offers a more convenient and long-lasting therapeutic option to manage diabetes and treat metabolic disorders.
Why this rating
Based on the innovative approach to therapy described in the abstract.
Source
Engineering Supramolecular Nanofiber Depots from a Glucagon-Like Peptide-1 Therapeutic
Weike Chen et al. · ACS Nano · 2024
DOI 10.1021/acsnano.4c10248
otherCited 6×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- The supramolecular GLP-1 receptor agonist (PA-GLP1) formulation achieved sustained serum concentrations for at least 40 days in a rat model of type 2 diabetes.Strong
- The PA-GLP1 formulation resulted in an overall reduction in blood glucose levels and reduced weight gain compared to daily injections of semaglutide.Strong
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