Research
Molecular
Higher genetic GLP1R gene expression is associated with a lower risk of kidney disease progression (HR, 0.96; P = .02).
Practitioners may consider the role of GLP1R gene expression in managing kidney disease risk.
StrongSupportsmedium confidence
Overall, higher genetic GLP1R gene expression was associated with a lower risk of kidney disease progression in the unadjusted model (hazard ratio [HR], 0.96; 95% CI, 0.92-0.99; P = .02).
Why this rating
Based on a large genetic association study with a significant sample size.
Source
<i>GLP1R</i> Gene Expression and Kidney Disease Progression
Jefferson L. Triozzi et al. · JAMA Network Open · 2024
cohort · n=353153Cited 6×
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