Research
Molecular
Higher GLP1R gene expression is associated with a small reduction in risk of kidney disease progression in fully adjusted models (HR, 0.96; P = .04).
This suggests that monitoring GLP1R gene expression could be relevant in kidney disease management.
StrongSupportsmedium confidence
In the fully adjusted model accounting for baseline patient characteristics, body mass index, and the presence or absence of diabetes (HR, 0.96; 95% CI, 0.92-1.00; P = .04).
Why this rating
The study design includes a large cohort with robust statistical analysis.
Source
<i>GLP1R</i> Gene Expression and Kidney Disease Progression
Jefferson L. Triozzi et al. · JAMA Network Open · 2024
cohort · n=353153Cited 6×
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