Research
Energy balance
There was no consistent impact of n-3-PUFA supplementation on functional outcome measures.
Functional improvements should not be expected from n-3-PUFA supplementation.
StrongRefutesmedium confidence
There was no consistent impact of n-3-PUFA supplementation on functional outcome measures.
Why this rating
Based on the overview of systematic reviews.
Source
Lack of evidence for Omega-3 fatty acid supplementation in enhancing lean mass, muscle strength, and physical function in healthy adults and clinical populations: An overview of reviews
Everson Araújo Nunes et al. · Clinical Nutrition ESPEN · 2025
DOI 10.1016/j.clnesp.2025.03.012
Meta-analysisCited 5×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- There is limited evidence supporting the effectiveness of n-3-PUFA supplementation in improving or preventing loss of lean mass in both younger and older healthy adults, as well as clinical populations including oncologic patients.Strong
- Most systematic reviews concluded that n-3-PUFA supplementation did not significantly affect strength.Strong
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