Research
Energy balance
Calorie restriction does not significantly interact with BMI stratum in affecting cognitive outcomes.
BMI does not appear to influence the cognitive effects of CR in this study.
StrongRefutesmedium confidence
nor a significant interaction between intervention and BMI stratum.
Why this rating
Based on a multi-center, randomized controlled trial design.
Source
CALERIE II: the effect of 25% calorie restriction over two years on cognitive function (629.7)
Tammy Scott et al. · The FASEB Journal · 2014
DOI 10.1096/fasebj.28.1_supplement.629.7
rct · n=218Cited 5×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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