Research
Energy balance
No statistically significant associations were identified for SGLT2 inhibitors regarding hematologic malignancy risk.
SGLT2 inhibitors may not pose a risk for hematologic malignancies, making them a safer choice in this regard.
StrongRefutesmedium confidence
No statistically significant associations were identified for SGLT2 inhibitors (i.e., 95%CI across 1.0).
Why this rating
Based on a pilot network meta-analysis of randomized controlled trials.
Source
Divergent Risks of Hematologic Malignancies Associated with GLP-1 Receptor Agonists and SGLT2 Inhibitors: Preliminary Findings from a Pilot Network Meta-Analysis
Pao‐Yen Lin et al. · Biomolecules · 2025
DOI 10.3390/biom15111622
Meta-analysisCited 5×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
Related findings · Energy balance
- Achieving a total body weight loss of 10-15% (or >10-15 kg) through Total Diet Replacement (TDR) induces remission of Type 2 Diabetes in individuals with short-duration disease.Strong
- Bariatric surgery is superior to medical management alone for inducing significant long-term weight loss, remission of type 2 diabetes, and reduction in mortality for patients with BMI ≥ 40 or ≥ 35 with comorbidities.Strong
- Achieving type 2 diabetes remission requires significant weight loss (≥15 kg) via major caloric restriction, independent of macronutrient composition.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →