Research
Cellular
Tirzepatide is linked to a significantly reduced risk of overall hematologic malignancy (OR = 0.14, 95%CI = 0.03-0.60), particularly for lymphoma.
Tirzepatide may be a safer option for patients concerned about hematologic malignancies.
StrongSupportsmedium confidence
In contrast, tirzepatide was linked to a significantly reduced risk (OR = 0.14, 95%CI = 0.03-0.60), especially for lymphoma.
Why this rating
Based on a pilot network meta-analysis of randomized controlled trials.
Source
Divergent Risks of Hematologic Malignancies Associated with GLP-1 Receptor Agonists and SGLT2 Inhibitors: Preliminary Findings from a Pilot Network Meta-Analysis
Pao‐Yen Lin et al. · Biomolecules · 2025
DOI 10.3390/biom15111622
Meta-analysisCited 5×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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