Research
Metabolic adaptation
A significant decrease in BMI (p=0.003), waist circumference (p=0.002), systolic (p=0.025) and diastolic blood pressure (p=0.007) and total cholesterol (p=0.026) and increase in HDL cholesterol (p=0.001) and oral disposition index (Dio)(p<0.001) was observed in controls after the diet.
A ketogenic diet may also benefit metabolic health in individuals without Cushing's disease.
StrongSupportsmedium confidence
A significant decrease in BMI (p=0.003), WC (p=0.002), systolic (p=0.025) and diastolic (p=0.007) blood pressure and total cholesterol (p=0.026) and increase in HDL cholesterol (p=0.001) and DIo (p<0.001) was observed in controls.
Why this rating
The study design allows for comparison between patients and controls.
Source
Nutritional Intervention in Cushing’s Disease: The Ketogenic Diet Effects on Metabolic Comorbidities and Adrenal Steroids
Valentina Guarnotta et al. · Preprints.org · 2023
cohort · n=30Cited 6×
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