Research
Energy balance
AOM-naïve patients experienced superior weight loss outcomes with semaglutide compared to non-AOM-naïve patients at 3, 6, 9, and 12 months.
Practitioners should consider that patients who have not previously used anti-obesity medications may achieve better weight loss results with semaglutide.
StrongSupportsmedium confidence
Outcomes of semaglutide treatment were superior in AOM-naïve patients (n = 231) compared to non-AOM-naïve patients (n = 74) at 3 (6.3% vs. 3.8%), 6 (10.6% vs. 6.7%), 9 (14.0% vs. 9.1%) and 12 months (14.3% vs. 10.6%; p < 0.0001 at 3, 6 and 9 months, and p = 0.01 at 12 months).
Why this rating
Based on the retrospective study design with a substantial sample size.
Source
The association between previous use of <scp>anti‐obesity</scp> medication and semaglutide weight loss outcomes
Wissam Ghusn et al. · Diabetes Obesity and Metabolism · 2024
cohort · n=305Cited 5×
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