Research
Metabolic adaptation
Energy restriction (ER) affects multiple metabolic, physiological, genetic, and cellular adaptation pathways associated with prolonged lifespan.
Practitioners should consider the potential lifespan benefits of energy restriction.
WeakSupportsmedium confidence
ER affects multiple metabolic, physiological, genetic, and cellular adaptation pathways associated with prolonged lifespan.
Why this rating
The claim is based on preclinical studies, which are less robust than human studies.
Source
Energy restriction or improvements in diet quality: identifying the best pathway for a longer and healthier life
Syed Imran Ahmed et al. · Minerva Cardiology and Angiology · 2023
DOI 10.23736/s2724-5683.23.06298-1
reviewCited 5×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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