Research
Metabolic adaptation
Ninety-day medical complications were significantly reduced in GLP-1 RA users across BMI categories ≥25.
Practitioners may consider GLP-1 RA use to reduce post-operative complications in obese patients.
StrongSupportsmedium confidence
Ninety-day medical complications-such as infection, pneumonia, thromboembolism, sepsis, stroke, and UTI-were significantly reduced in GLP-1 RA users across BMI categories ≥25.
Why this rating
Based on a large retrospective cohort study.
Source
Association of Glucagon-Like Peptide-1 Receptor Agonist Use With Complications Following Thoracic and/or Lumbar Spinal Fusion for Degenerative Spine Disease
Arman Kishan et al. · Spine · 2025
DOI 10.1097/brs.0000000000005494
cohort · n=291677Cited 4×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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