Research
Metabolic adaptation
Two-year surgical complications were lower among GLP-1 RA users in BMI 35 to 39.9 and ≥40 groups.
GLP-1 RA may be beneficial for reducing long-term surgical complications in higher BMI patients.
StrongSupportsmedium confidence
Two-year surgical complications were lower among GLP-1 RA users in BMI 35 ti 39.9 (1.1% vs . 1.6%, P =0.007 for pseudarthrosis-related revision; 0.8% vs . 1.2%, P =0.038 for mechanical failure) and ≥40 groups.
Why this rating
Based on a large retrospective cohort study.
Source
Association of Glucagon-Like Peptide-1 Receptor Agonist Use With Complications Following Thoracic and/or Lumbar Spinal Fusion for Degenerative Spine Disease
Arman Kishan et al. · Spine · 2025
cohort · n=291677Cited 4×
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