Research
Metabolic adaptation
Semaglutide users had higher rates of pneumonia (2.97 % vs 0.85 %, p < 0.05) compared to non-users.
Clinicians should be aware of the increased risk of pneumonia in patients using semaglutide.
StrongSupportsmedium confidence
Semaglutide users had higher rates of pneumonia (2.97 % vs 0.85 %, p < 0.05) compared to nonusers.
Why this rating
Based on a retrospective analysis with matched controls.
Source
The impact of semaglutide use for weight loss on transforaminal lumbar interbody fusion outcomes
Syed Khalid et al. · Clinical Neurology and Neurosurgery · 2025
DOI 10.1016/j.clineuro.2025.108952
other · n=942Cited 4×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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- Patients with longer semaglutide use had a higher incidence of urinary tract infection (4.03 % vs 1.27 %, p < 0.05) and acute kidney injury (3.18 % vs 0.85 %, p < 0.05).Strong
- The need for additional lumbar fusion was associated with both semaglutide use (17.0 % vs. 6.4 %, p < 0.0001) and duration (28.3 % vs. 4.8 %, p < 0.0001).Strong
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