Research
Metabolic adaptation
The need for additional lumbar fusion was associated with both semaglutide use (17.0 % vs. 6.4 %, p < 0.0001) and duration (28.3 % vs. 4.8 %, p < 0.0001).
Surgeons should consider the potential for increased surgical interventions in patients using semaglutide.
StrongSupportsmedium confidence
The need for additional lumbar fusion was associated with both semaglutide use (17.0 % vs. 6.4 %, p < 0.0001) and duration (28.3 % vs. 4.8 %, p < 0.0001).
Why this rating
Based on a retrospective analysis with matched controls.
Source
The impact of semaglutide use for weight loss on transforaminal lumbar interbody fusion outcomes
Syed Khalid et al. · Clinical Neurology and Neurosurgery · 2025
other · n=942Cited 4×
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