Browse the evidence

Carotid cross-sectional compliance, beta-stiffness index, intima-media thickness, and cardiac dimensions remained unchanged after 12 weeks of resistance training.

Resistance training does not appear to affect certain vascular and cardiac parameters in young men.

Participants with microvascular disease (MVD) have a 2.5-fold higher risk of incident heart failure (HF) than those without MVD.

Healthcare providers should monitor heart health closely in patients with MVD.

MitoQ supplementation did not impact mitochondrial respiration or H2O2 emission in the presence of ADP.

MitoQ does not enhance mitochondrial function during exercise in older adults.

MitoQ supplementation did not alter acute exercise-induced redox responses in skeletal muscle.

MitoQ does not affect redox signaling during acute exercise in older adults.

HbA1C levels increase alongside the duration of illness in individuals with type 2 diabetes.

Practitioners should monitor HbA1C levels to assess disease progression in diabetic patients.

ALA intake reduces the incidence of coronary heart disease (CHD).

Practitioners may consider recommending ALA-rich foods for reducing CHD risk.

Recommendations for modest dietary consumption of ALA (2 to 3 g per day) are favored for CHD prevention.

Practitioners should consider advising patients to include 2 to 3 g of ALA in their diets.

Observational data suggest GLP-1 RAs improve walking distance in peripheral artery disease.

GLP-1 RAs may enhance mobility in patients with peripheral artery disease.

Nutritional therapists are too rarely consulted despite the significant effects of diet on cardiovascular risk factors.

Practitioners should consider involving nutritional therapists in treatment plans for dyslipidemias.

Intake of red meat is associated with an elevated risk of colon cancer (relative risk, 1.71; 95% CI, 1.15-2.55).

Practitioners should consider advising patients to limit red meat intake to reduce colon cancer risk.

Consumption of caffeinated coffee decreases the risk of kidney stone formation by 10% for each 240-ml serving consumed daily.

Encouraging the consumption of caffeinated coffee may help reduce the risk of kidney stones.

Consumption of apple juice increases the risk of kidney stone formation by 35% for each 240-ml serving consumed daily.

Limiting apple juice consumption may help reduce the risk of kidney stones.

Tirzepatide may result in an increase in non-serious adverse events (risk ratio 1.33, 95% CI 1.03 to 1.71) compared to placebo.

Clinicians should monitor for non-serious adverse events when prescribing tirzepatide.

Incretin therapies could ameliorate fatty liver disease, chronic inflammation, sleep apnea, and possibly degenerative bone disorders and cognitive decline.

Incretin therapies may be considered for patients with these co-morbidities, pending further research.

Baseline disease severity, depressive symptoms, insulin resistance, and preperitoneal fat were negatively associated with PASI improvement.

Understanding these associations can help tailor treatment strategies for better outcomes.

Tirzepatide may have potential therapeutic effects on metabolic dysfunction-associated steatohepatitis (MASH).

Tirzepatide could be explored as a treatment option for patients with MASH, pending further research.

Heavier drinking (30 g or more per day) is associated with an increased risk of death from causes such as breast cancer and cirrhosis.

Practitioners should caution against heavy alcohol consumption due to associated health risks.

The relationship between weight modification after bariatric surgery and blood pressure measurement could provide insights into the mechanisms of organ damage associated with elevated blood pressure in obesity.

Further research is needed to explore the mechanisms of BP-related organ damage in obese patients post-surgery.

Consumption of beer decreases the risk of kidney stone formation by 21% for each 240-ml serving consumed daily.

Encouraging the consumption of beer may help reduce the risk of kidney stones.

High bodyweight variability was significantly associated with an increased risk of psoriasis, with a hazard ratio of 1.06 (1.05-1.07) comparing the highest quartile (Q4) to the lowest quartile (Q1).

Clinicians should encourage patients to maintain stable bodyweight to help prevent psoriasis.

Mechanistic studies may explain the cardiovascular benefits of SGLT2 inhibition in T2DM patients.

Practitioners should consider the underlying mechanisms when evaluating the cardiovascular benefits of SGLT2 inhibitors.

No changes regarding the inflammatory state were observed after the cardiac rehabilitation program.

Cardiac rehabilitation may not affect inflammatory markers in patients with cardiovascular disease.

Stacking supplements can be a deliberate strategy to maximize results in athletes.

Athletes may consider strategic stacking of supplements to enhance performance.

Increased consumption of dietary supplements is significantly related to poor oral health among amateur bodybuilders and powerlifters.

Practitioners should be aware of the potential negative effects of dietary supplements on oral health in this population.