Research
Cellular
Mechanistic studies may explain the cardiovascular benefits of SGLT2 inhibition in T2DM patients.
Practitioners should consider the underlying mechanisms when evaluating the cardiovascular benefits of SGLT2 inhibitors.
GoodQualifiesmedium confidence
We also review the mechanistic studies that might explain the CV benefits of SGLT2 inhibition in patients with T2DM.
Why this rating
The claim is based on a review of mechanistic studies, which are generally less robust than large-scale trials.
Source
Sodium–Glucose Cotransporter-2 Inhibition in Type 2 Diabetes Mellitus
Rinkoo Dalan · Cardiology in Review · 2018
DOI 10.1097/crd.0000000000000201
reviewCited 5×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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