Browse the evidence

Recent findings highlight promising signaling/targets for managing body weight, including appetite inhibition and energy expenditure.

Practitioners should focus on these signaling pathways for obesity interventions.

Weight loss in the GLP-1 RA group was directly associated with bone loss at the total hip (TH) and femoral neck (FN).

Weight management strategies may need to consider potential impacts on bone health.

The PMR diet was found to be safe, with no adverse events attributed to study participation.

The PMR diet can be safely implemented in clinical settings for stroke patients.

Participants in the PMR group reported barriers to weight loss, including food cravings and dislike for some food products.

Addressing food preferences and cravings may enhance adherence to PMR diets.

Roux-en-Y gastric bypass was associated with less gastroesophageal reflux disease (GERD)-related symptoms compared to sleeve gastrectomy.

Surgeons may prefer Roux-en-Y gastric bypass for patients concerned about GERD symptoms.

Traditional resistance training and blood flow restriction training showed conflicting results for improving quadriceps size.

Practitioners should be cautious when applying traditional resistance and blood flow restriction training due to inconsistent outcomes.

Physical activity contributes principally to the maintenance of weight loss rather than the induction of weight loss.

Emphasize physical activity for maintaining weight loss in treatment plans.

The study suggests that patient-delivered interventions may be effective in community and clinical settings for weight loss maintenance.

Consider exploring patient-delivered interventions in various settings for effective weight maintenance.

Male individuals lost a significantly larger proportion of weight as lean soft tissue (LST) compared to female individuals, with means of 0.33 kg and 0.25 kg respectively.

Practitioners should consider gender differences in body composition changes during weight loss interventions.

Quality of life outcomes generally showed improvements with incretin-based therapies (IBTs).

Clinicians can expect improvements in quality of life for patients using IBTs.

Fresh bread and rice consumption are associated with lower IBD risk.

Encouraging the consumption of fresh bread and rice may be beneficial for gut health.

Understanding patient concerns about the risks of obesity treatment is essential to addressing obesity treatment inertia.

Addressing these concerns may help improve treatment adherence and outcomes.

Baseline body fat percentage was significantly associated with weight gains (r = 0.57) and fat mass gains (r = 0.59) during an 8-week high-fat overfeeding intervention.

Practitioners should consider baseline body fat percentage when assessing weight gain responses to overfeeding.

Body fat percentage was inversely associated with the energy cost of weight (r = -0.38) and fat mass (r = -0.40) gains.

Higher body fat percentage may indicate lower energy efficiency in gaining weight.

Semaglutide users experienced modest weight reductions ranging from 0.42 kg to 1.16 kg.

Practitioners may consider Semaglutide for modest weight loss in type 2 diabetes management.

The study identified key themes for safe practices in BMT, including psychological health, sleep apnea, cardiovascular disease, liver health, and dietetic assessment.

Practitioners should consider these health factors when evaluating patients for BMT.

The introduction of a Disease Management Program for obesity could significantly improve the quality of care for affected individuals.

Implementing a Disease Management Program could enhance care quality for individuals with obesity.

Prevention of overweight and obesity is crucial and should be addressed socially.

Efforts to prevent obesity should involve community and societal strategies.

Lacto-ovo-vegetarians had lower protein consumption than non-vegetarians throughout the study but still achieved adequate protein intake.

Adequate protein intake can be achieved even with lower consumption in vegetarians.

Innovative solutions are needed to implement sustainable lifestyle modification interventions for T2D.

Practitioners should advocate for and develop innovative strategies to enhance lifestyle intervention adherence.

Efficient lipid-lowering drugs have substantially reduced the incidence and mortality for cardiovascular disease (CVD).

Practitioners should consider lipid-lowering drugs as effective interventions for reducing CVD risk.

Obesity increases the risk of postoperative complications following elective surgery.

Surgeons should consider obesity as a significant risk factor when planning surgeries.

An interdisciplinary approach is necessary for effective weight loss treatment in obese patients before joint replacement surgery.

Healthcare teams should collaborate across disciplines to optimize weight loss strategies for these patients.

Diabetic patients had a significantly higher percentage excess weight loss (%EWL) than nondiabetics at 12 and 24 months post LSG.

Diabetic patients undergoing LSG may experience greater weight loss compared to nondiabetic patients, which can inform clinical expectations.