Browse the evidence

Nutritional intake guidelines can be individualized to target multiple long-term conditions.

Nutrition plans should be customized to address specific health conditions.

CLA supplementation is associated with increased muscle variables or decreased adiposity variables.

CLA may be beneficial for individuals looking to improve muscle mass or reduce fat.

Body composition improved with losses in fat mass and gains in overall proportion of lean muscle and skeletal muscle.

Practitioners can expect improvements in body composition with semaglutide treatment.

Advances in metabolic surgery, pharmacologic therapy, and lifestyle modification have made remission of diabetes more feasible.

Healthcare providers should consider these advancements when discussing treatment options.

Meal replacement (MR) significantly reduced glycated hemoglobin A1c (HbA1c) by -0.46%, fasting blood glucose (FBG) by -0.62 mmol/L, body weight by -2.43 kg, and body mass index (BMI) by -0.65 compared to conventional diabetic diets (CDs).

Implementing meal replacement strategies can lead to significant improvements in glycemic control and weight management for T2D patients.

Total meal replacement showed greater improvement in HbA1c, FBG, body weight, and BMI compared to partial meal replacement.

Total meal replacement may be more effective than partial meal replacement for improving health markers in T2D patients.

Evidence-based nutritional and lifestyle strategies are crucial for effective GLP-1 treatment.

Clinicians should integrate nutritional and lifestyle interventions to enhance GLP-1 treatment outcomes.

Resistance exercises seem to be beneficial for patients with type 1 diabetes.

Healthcare providers should consider recommending resistance training for patients with type 1 diabetes.

ADA/ISPAD goal achievement was associated with greater cardiopulmonary fitness, with VO2peak values significantly higher in those meeting more goals.

Practitioners should promote achieving ADA/ISPAD goals to enhance cardiopulmonary fitness in adolescents with type 1 diabetes.

Dietary energy intake and macronutrient ratios should be manipulated to optimize muscular adaptations.

Athletes should adjust their diet to enhance muscle growth effectively.

Weight loss can improve obesity-related comorbidities such as metabolic syndrome, diabetes, cardiovascular disease, and obstructive sleep apnea.

Weight loss should be emphasized in preoperative counseling for patients with obesity.

Diabetes remission occurred in five GB participants and no medical participants (relative risk 0.76, 95% CI: 0.55-0.93, p = .048).

GB surgery may increase the likelihood of diabetes remission in overweight individuals with type 2 diabetes.

Adherence to the Mediterranean diet is associated with improved control of cardiovascular risk factors.

Encouraging adherence to the Mediterranean diet may help improve cardiovascular health in diabetic patients.

Intermittent energy restriction methodologies such as refeeds and diet breaks may improve fat loss efficiency, lean body mass retention, and attenuate metabolic adaptation to weight loss.

Practitioners may consider incorporating refeeds and diet breaks into competition preparation strategies.

Weight-lowering approaches such as bariatric surgery and treatment with semaglutide and tirzepatide can alleviate both cardiovascular diseases (CVD) and nonalcoholic fatty liver disease (NAFLD).

Practitioners should consider weight loss interventions as effective strategies for managing NAFLD and CVD.

A minimal amount of weight loss can resolve NAFLD in lean patients.

Even small weight loss should be encouraged in lean patients with NAFLD for potential resolution of the condition.

Obesity significantly increases the risk of both nonalcoholic fatty liver disease (NAFLD) and cardiovascular diseases (CVD).

Addressing obesity is crucial for reducing the risk of NAFLD and CVD in patients.

Exercise is a key component of lifestyle therapy for prevention and treatment of diabetes.

Practitioners should incorporate exercise into diabetes management plans.

Diets that restrict certain macronutrients may be better for controlling weight and metabolic risk factors.

Consider advising patients on diets with specific macronutrient restrictions for better outcomes.

Exercise is a well-established measure to prevent or mitigate the adverse consequences of obesity.

Encouraging exercise can be a key strategy in obesity management.

Diets that restrict certain macronutrients may be better for controlling weight and metabolic risk factors.

Consider exploring macronutrient-restricted diets for better weight and metabolic control in patients.

Rest interval durations of 60 seconds and 120 seconds between sets favored a higher total load lifted in the exercise session compared to the 30 seconds rest interval.

Practitioners should consider longer rest intervals (60-120 seconds) to maximize load lifted during resistance training.

Intensive lifestyle interventions (ILIs) are preferred over anti-hyperglycemic medications for the prevention of type 2 diabetes (T2D) due to their safety, efficacy, and cost.

Practitioners should prioritize ILIs for T2D prevention in overweight/obese patients.

Offering intensive lifestyle interventions to all overweight/obese adults who volunteer for weight loss treatment may be a more effective approach to prevent type 2 diabetes.

Consider broadening eligibility for ILIs to enhance participation in weight loss programs.